Dr. John Augustine received his BA from Harvard College magna cum laude in 1987 and his Ph.D. and MD degrees from the Albert Einstein College of Medicine in 1992 and 1993. He was then an intern and resident in Internal Medicine at the Yale-New Haven Hospital from 1993-1995. From 1995-1998, John was a clinical associate at the National Cancer Institute. He joined the faculty of the Duke University Medical Center in 2008 as Chief of Rheumatology at the Durham VA Hospital, a position he held until the end of 2017. He served as Chief of Rheumatology and Immunology at Duke from 2003-2008. He has conducted basic and translational research in the field of autoimmunity. He was focusing on the pathogenesis of systemic lupus erythematosus (SLE) and the immunological properties of nuclear macromolecules, including DNA. More recently, he has investigated the immune activities of HMGB1, a nuclear protein with alarmin activity, as well as microparticles. These studies have provided new insights into the translocation of atomic molecules during cell activation and cell death and the mechanisms by which cell death can influence innate immunity.